AlphaFold
DeepMind's AI that solved a 50-year-old biology grand challenge: predicting protein 3D structure from amino-acid sequence.
AlphaFold 2 (2020) broke through on the CASP (Critical Assessment of protein Structure Prediction) benchmark. AF3 (2024) handles protein-DNA-RNA interactions. Changes drug discovery. Nobel Prize 2024 for Demis Hassabis and John Jumper.